Activon Tube 100% Medical Grade Manuka honey 25g

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Activon Tube contains 100% Manuka honey with no additives from New Zealand. Our Manuka honey is filtered and sterilised, making it suitable for application to wounds. Manuka honey will de-bride and de-slough, eliminate odours and provides a moist wound healing environment.

Activon Tube is ideal for debriding necrotic tissue, or for topping up dressings where the honey has been washed away by exudate. Great for using in cavities, just wash away with saline solution.



Manuka honey brings the following properties:

  • Anti-bacterial, effectively kills harmful bacteria
  • Anti-inflammatory
  • Eliminates odours without masking them
  • Osmotic effect, drawing harmful tissue away from the wound bed
  • Maintains the ideal moist wound healing environment


Twist off cap, apply liberally to the wound bed to a minimum depth of 5mm and cover with an appropriate secondary dressing. Activon Tube is a single patient use only product, once opened use within 4 days.

Initially you may experience high levels of exudate, this is perfectly normal and will decrease over time, therefore your secondary dressing of choice may initially need to be super absorbent, we recommend Eclypse.

Top tip

Use Activon Tube in conjunction with Algivon for debriding and de-sloughing.


Activon Tube is ideal for debriding necrotic tissue; it’s ideal for topping up dressings where the honey is washed away or great for using directly into cavities. Honey can be washed away using normal saline solution. As honey is a natural product any remaining honey will not have any adverse effects.

Activon Tube may be applied to any wound but especially: Pressure ulcers, leg ulcers, diabetic ulcers, surgical wounds, burns, graft sites, infected wounds, cavity wounds and sinuses

Browse case studies using Activon Tube


Although the honey is not absorbed into the blood stream, we advise monitoring the levels of patients with diabetes. Do not use if allergic to bee venom.

Discomfort can be experienced when honey is applied, depending on sensitivity of the wound it may be necessary to consider an appropriate level of analgesic. The initial discomfort usually subsides, however if it does continue, discontinue use and irrigate the wound with saline solution.

Manuka honey FAQ's

Can your Manuka honey dressings be used on diabetic patients?

While there is no known case of honey influencing blood glucose levels adversely, it is recommended that the blood sugar levels of patients with diabetes are monitored when using honey.

Can the Activon Tulle be unfolded to apply?

Activon Tulle can be unfolded and applied, however this will reduce the level of honey at the wound bed. The triple layer of the gauze delivers the optimum amount of honey to the wound bed therefore unfolding the dressing would affect efficacy.

Can Activon honey be used under compression bandaging?

The Activon range can be used under compression bandaging. The amount of exudate would influence your choice of Algivon, Activon Tulle or Actilite with an appropriate absorbent secondary dressing such as Eclypse. As compression bandaging is ideally designed to be left in place for a full week Algivon may be appropriate due to the fact that, in the presence of exudate, the alginate fibres swell, forming a sodium-calcium gel on their surface which combines with the honey. The resulting honey-gel complex prolongs the retention of honey at the wound site, increasing effectiveness. The secondary dressing must be appropriate to the exudate level and will influence wear time.

Does the honey sting on application?

There have been reports of honey causing a stinging pain when applied to the wound. This appears to be due to the acidity of honey, as pain is not experienced when neutralised honey is used. The pain experienced does not seem to be indicative of damage being done to the wound, as wounds have healed rapidly in cases where patients have endured the pain to benefit from the stimulation of healing that they see, and in cases where analgesia has been used. There is evidence that honey stimulates nocioceptors (Al-Swayeh and Ali, 1998), nerve endings that create a pain sensation in response to heat, acidity and some organic chemicals. It may be that it is not a direct effect of the acidity of honey, as neutralising honey could affect the ionisation of some of its components and make them unable to fit in the nocioceptors. It is possible that in some patients these nerve endings are sensitised and are more responsive to the acidity and/or the component organic chemicals of honey.

What are the contra indications for your Manuka honey?

Known allergy to bee-venom. Although no known instance of increased levels of blood sugar in patients with diabetes. It is advisable to closely monitor the levels. Increased pain may be experienced due to acidification.

How long can the honey dressings be left on the wound for?

The dressings can be left in place for up to seven days, again this would depend on the exudate levels produced by the wound and the appearance of the dressing. As long as the dressing has maintained it’s original colour (the honey is present) it can remain in situ.

Can Activon Tulle or Algivon be folded and put into a cavity?

Both dressings could be put into a cavity wound, again dependant on exudate levels. If there is a possibility of sinus within the wound base then Activon Tube should be used to ensure that the honey reaches the entire wound bed.

What happens to the exudate when Algivon is being used?

Algivon contains calcium alginate which forms a gel when in contact with exudate however an appropriate secondary absorbent dressing will be required such as Eclypse or Eclypse Adherent.

How do you know whether to use Algivon or Activon Tulle?

This would be dependant on the grade of wound and the level of exudate. In a heavily exuding or necrotic wound your choice would be Algivon however if the wound is producing moderate exudate then Activon Tulle would be the dressing

Advanced wound care - It's all we do and everything we do.

Advancis Medical is a UK based medical device company building an international reputation for developing, manufacturing and marketing a range of advanced wound care products.

Our mission

To design, develop and provide clinical advantages using unique and innovative products whilst offering a commercial benefit to health care professionals.

How we work

Whether we are working with clinicians, nurses, carers or our own team we always put the needs of the patient first. It is our commitment to people that drives our principles:


  • Reduced healing times
  • Maximise patient comfort
  • Provide cost effective solutions for healthcare professionals
  • Improved patient outcomes
  • Ongoing and continuous products development
  • Commitment to development and education of our people

Our history

Our company was the first to introduce medical grade Manuka honey as a medical device into the UK. Since 2004 we have been working with some of the worlds leading experts in their field, patients and their carers, to develop solutions to wound management challenges. Our range has been expanded to use the latest advances in material technology and now includes soft silicone atraumatic dressings, super absorbent dressings designed to handle high levels of exudate and fluid and our hydrophilic foam dressing range launched in 2011.

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